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Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase
The highly mutagenic A:8-oxoguanine (oxoG) base pair is generated mainly by misreplication of the C:oxoG base pair, the oxidation product of the C:G base pair. The A:oxoG base pair is particularly insidious because neither base in it carries faithful information to direct the repair of the other. Th...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5377813/ https://ncbi.nlm.nih.gov/pubmed/28130451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757039 |
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