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Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase

The highly mutagenic A:8-oxoguanine (oxoG) base pair is generated mainly by misreplication of the C:oxoG base pair, the oxidation product of the C:G base pair. The A:oxoG base pair is particularly insidious because neither base in it carries faithful information to direct the repair of the other. Th...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Wang, Lan, Chakravarthy, Srinivas, Verdine, Gregory L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377813/
https://ncbi.nlm.nih.gov/pubmed/28130451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757039
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