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Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase

Adenine DNA glycosylase catalyzes the glycolytic removal of adenine from the promutagenic A·oxoG base pair in DNA. The general features of DNA recognition by an adenine DNA glycosylase, Bacillus stearothermophilus MutY, have previously been revealed via the X-ray structure of a catalytically inactiv...

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Detalhes bibliográficos
Main Authors: Lee, Seongmin, Verdine, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773975/
https://ncbi.nlm.nih.gov/pubmed/19841264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902908106
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