Genome-wide analysis links NFATC2 with asparaginase hypersensitivity

Asparaginase is used to treat acute lymphoblastic leukemia (ALL); however, hypersensitivity reactions can lead to suboptimal asparaginase exposure. Our objective was to use a genome-wide approach to identify loci associated with asparaginase hypersensitivity in children with ALL enrolled on St. Jude...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Blood
المؤلفون الرئيسيون: Fernandez, Christian A., Smith, Colton, Yang, Wenjian, Mullighan, Charles G., Qu, Chunxu, Larsen, Eric, Bowman, W. Paul, Liu, Chengcheng, Ramsey, Laura B., Chang, Tamara, Karol, Seth E., Loh, Mignon L., Raetz, Elizabeth A., Winick, Naomi J., Hunger, Stephen P., Carroll, William L., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Devidas, Meenakshi, Relling, Mary V.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Hematology 2015
الموضوعات:
Lymphoid Neoplasia
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492197/
https://ncbi.nlm.nih.gov/pubmed/25987655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-628800
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