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Higher Plasma Asparaginase Activity after Intramuscular than Intravenous Erwinia Asparaginase
It is unclear if dosing intervals for Erwinase can be extended with intramuscular (IM) vs intravenous (IV) dosing. Children with acute lymphoblastic leukemia received Erwinase at 30,000–42,000 IU/m(2) IV or IM. IM Erwinase (n=22) achieved activity above 0.1 IU/mL for longer than IV Erwinase (n=33) (...
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| Izdano u: | Pediatr Blood Cancer |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7253324/ https://ncbi.nlm.nih.gov/pubmed/32323890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.28244 |
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