Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia

BACKGROUND: Glucocorticoids and asparaginase, used to treat acute lymphoblastic leukemia (ALL), can cause hypertriglyceridemia. We compared triglyceride levels, risk factors, and associated toxicities in two ALL trials at St. Jude Children’s Research Hospital with identical glucocorticoid regimens,...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Finch, Emily R., Smith, Colton A., Yang, Wenjian, Liu, Yiwei, Kornegay, Nancy M., Panetta, John C., Crews, Kristine R., Molinelli, Alejandro R., Cheng, Cheng, Pei, Deqing, Ramsey, Laura B., Karol, Seth E., Inaba, Hiroto, Sandlund, John T., Metzger, Monika, Evans, William E., Jeha, Sima, Pui, Ching-Hon, Relling, Mary V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868303/
https://ncbi.nlm.nih.gov/pubmed/31612640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.28040
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