Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia

Hypersensitivity to asparaginase is common but the differential diagnosis can be challenging, and the diagnostic utility of antibody tests is unclear. We studied allergic reactions and serum antibodies to E. coli-asparaginase (Elspar) in 410 children treated on St. Jude Total XV protocol for acute l...

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Autori principali: Liu, Chengcheng, Kawedia, Jitesh D., Cheng, Cheng, Pei, Deqing, Fernandez, Christian A., Cai, Xiangjun, Crews, Kristine R., Kaste, Sue C., Panetta, John C., Bowman, W. Paul, Jeha, Sima, Sandlund, John T., Evans, William E., Pui, Ching-Hon, Relling, Mary V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516853/
https://ncbi.nlm.nih.gov/pubmed/22484422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.102
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