Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity

A murine model was developed that recapitulates key features of clinical hypersensitivity to Escherichia coli asparaginase. Sensitized mice developed high levels of anti-asparaginase IgG antibodies and had immediate hypersensitivity reactions to asparaginase upon challenge. Sensitized mice had compl...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:J Pharmacol Exp Ther
Główni autorzy: Fernandez, Christian A., Smith, Colton, Karol, Seth E., Ramsey, Laura B., Liu, Chengcheng, Pui, Ching-Hon, Jeha, Sima, Evans, William E., Finkelman, Fred D., Relling, Mary V.
Format: Artigo
Język:Inglês
Wydane: The American Society for Pharmacology and Experimental Therapeutics 2015
Hasła przedmiotowe:
Chemotherapy, Antibiotics, and Gene Therapy
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352598/
https://ncbi.nlm.nih.gov/pubmed/25573198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.220780
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