Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity

A murine model was developed that recapitulates key features of clinical hypersensitivity to Escherichia coli asparaginase. Sensitized mice developed high levels of anti-asparaginase IgG antibodies and had immediate hypersensitivity reactions to asparaginase upon challenge. Sensitized mice had compl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharmacol Exp Ther
Prif Awduron: Fernandez, Christian A., Smith, Colton, Karol, Seth E., Ramsey, Laura B., Liu, Chengcheng, Pui, Ching-Hon, Jeha, Sima, Evans, William E., Finkelman, Fred D., Relling, Mary V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2015
Pynciau:
Chemotherapy, Antibiotics, and Gene Therapy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352598/
https://ncbi.nlm.nih.gov/pubmed/25573198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.220780
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg