Effect of Premedications in a Murine Model of Asparaginase Hypersensitivity

A murine model was developed that recapitulates key features of clinical hypersensitivity to Escherichia coli asparaginase. Sensitized mice developed high levels of anti-asparaginase IgG antibodies and had immediate hypersensitivity reactions to asparaginase upon challenge. Sensitized mice had compl...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Pharmacol Exp Ther
المؤلفون الرئيسيون: Fernandez, Christian A., Smith, Colton, Karol, Seth E., Ramsey, Laura B., Liu, Chengcheng, Pui, Ching-Hon, Jeha, Sima, Evans, William E., Finkelman, Fred D., Relling, Mary V.
التنسيق: Artigo
اللغة:Inglês
منشور في: The American Society for Pharmacology and Experimental Therapeutics 2015
الموضوعات:
Chemotherapy, Antibiotics, and Gene Therapy
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352598/
https://ncbi.nlm.nih.gov/pubmed/25573198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.220780
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