Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity

The genetic variations that lead to asparaginase allergy are unknown. We interrogated over 500,000 single nucleotide polymorphisms (SNPs) in 485 children with acute lymphoblastic leukemia (ALL): 322 in a discovery and 163 in a validation cohort. From the top 100 SNPs associated with allergy in the d...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Shih-Hsiang, Pei, Deqing, Yang, Wenjian, Cheng, Cheng, Jeha, Sima, Cox, Nancy J., Evans, William E., Pui, Ching-Hon, Relling, Mary V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000799/
https://ncbi.nlm.nih.gov/pubmed/20592726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2010.94
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