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Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis
Cells are protected from toxic DNA double-stranded breaks (DSBs) by a number of DNA repair mechanisms, including some that are intrinsically error prone, thus resulting in mutations. To what extent these mechanisms contribute to evolutionary diversification remains unknown. Here, we demonstrate that...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Pub. Group
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490562/ https://ncbi.nlm.nih.gov/pubmed/26077599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8394 |
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