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Mutational signatures of non‐homologous and polymerase theta‐mediated end‐joining in embryonic stem cells
Cells employ potentially mutagenic DNA repair mechanisms to avoid the detrimental effects of chromosome breaks on cell survival. While classical non‐homologous end‐joining (cNHEJ) is largely error‐free, alternative end‐joining pathways have been described that are intrinsically mutagenic. Which end‐...
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| Vydáno v: | EMBO J |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5730883/ https://ncbi.nlm.nih.gov/pubmed/29079701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201796948 |
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