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Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission

The HIV envelope glycoprotein gp120 contains nine disulphide bridges and is highly glycosylated, carrying on average 24 N-linked glycans. Using a probability calculation, we here demonstrate that there is a co-localization of disulphide bridges and N-linked glycans in HIV-1 gp120, with a predominanc...

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Publicado en:PLoS One
Autores principales: Mathys, Leen, Balzarini, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488071/
https://ncbi.nlm.nih.gov/pubmed/26121645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130621
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