The role of N-glycans of HIV-1 gp41 in virus infectivity and susceptibility to the suppressive effects of carbohydrate-binding agents

BACKGROUND: Carbohydrate-binding agents (CBAs) are potent antiretroviral compounds that target the N-glycans on the HIV-1 envelope glycoproteins. The development of phenotypic resistance to CBAs by the virus is accompanied by the deletion of multiple N-linked glycans of the surface envelope glycopro...

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Vydáno v:Retrovirology
Hlavní autoři: Mathys, Leen, Balzarini, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269863/
https://ncbi.nlm.nih.gov/pubmed/25499264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0107-7
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