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Sirolimus for progressive neurofibromatosis type 1–associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study

BACKGROUND: Plexiform neurofibromas (PNs) are benign peripheral nerve sheath tumors that arise in one-third of individuals with neurofibromatosis type 1 (NF1). They may cause significant disfigurement, compression of vital structures, neurologic dysfunction, and/or pain. Currently, the only effectiv...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Weiss, Brian, Widemann, Brigitte C., Wolters, Pamela, Dombi, Eva, Vinks, Alexander, Cantor, Alan, Perentesis, John, Schorry, Elizabeth, Ullrich, Nicole, Gutmann, David H., Tonsgard, James, Viskochil, David, Korf, Bruce, Packer, Roger J., Fisher, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483073/
https://ncbi.nlm.nih.gov/pubmed/25314964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou235
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