Sirolimus for progressive neurofibromatosis type 1–associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study

BACKGROUND: Plexiform neurofibromas (PNs) are benign peripheral nerve sheath tumors that arise in one-third of individuals with neurofibromatosis type 1 (NF1). They may cause significant disfigurement, compression of vital structures, neurologic dysfunction, and/or pain. Currently, the only effectiv...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Weiss, Brian, Widemann, Brigitte C., Wolters, Pamela, Dombi, Eva, Vinks, Alexander, Cantor, Alan, Perentesis, John, Schorry, Elizabeth, Ullrich, Nicole, Gutmann, David H., Tonsgard, James, Viskochil, David, Korf, Bruce, Packer, Roger J., Fisher, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Pediatric Neuro-Oncology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483073/
https://ncbi.nlm.nih.gov/pubmed/25314964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou235
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