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Sirolimus for progressive neurofibromatosis type 1–associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study

BACKGROUND: Plexiform neurofibromas (PNs) are benign peripheral nerve sheath tumors that arise in one-third of individuals with neurofibromatosis type 1 (NF1). They may cause significant disfigurement, compression of vital structures, neurologic dysfunction, and/or pain. Currently, the only effectiv...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Weiss, Brian, Widemann, Brigitte C., Wolters, Pamela, Dombi, Eva, Vinks, Alexander, Cantor, Alan, Perentesis, John, Schorry, Elizabeth, Ullrich, Nicole, Gutmann, David H., Tonsgard, James, Viskochil, David, Korf, Bruce, Packer, Roger J., Fisher, Michael J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483073/
https://ncbi.nlm.nih.gov/pubmed/25314964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou235
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