Sirolimus for progressive neurofibromatosis type 1–associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study

BACKGROUND: Plexiform neurofibromas (PNs) are benign peripheral nerve sheath tumors that arise in one-third of individuals with neurofibromatosis type 1 (NF1). They may cause significant disfigurement, compression of vital structures, neurologic dysfunction, and/or pain. Currently, the only effectiv...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Weiss, Brian, Widemann, Brigitte C., Wolters, Pamela, Dombi, Eva, Vinks, Alexander, Cantor, Alan, Perentesis, John, Schorry, Elizabeth, Ullrich, Nicole, Gutmann, David H., Tonsgard, James, Viskochil, David, Korf, Bruce, Packer, Roger J., Fisher, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Pediatric Neuro-Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483073/
https://ncbi.nlm.nih.gov/pubmed/25314964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou235
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