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Low Affinity and Slow Na(+) Binding Precedes High Affinity Aspartate Binding in the Secondary-active Transporter Glt(Ph)

Glt(Ph) from Pyrococcus horikoshii is a homotrimeric Na(+)-coupled aspartate transporter. It belongs to the widespread family of glutamate transporters, which also includes the mammalian excitatory amino acid transporters that take up the neurotransmitter glutamate. Each protomer in Glt(Ph) consists...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Hänelt, Inga, Jensen, Sonja, Wunnicke, Dorith, Slotboom, Dirk Jan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481202/
https://ncbi.nlm.nih.gov/pubmed/25922069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.656876
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