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Low Affinity and Slow Na(+) Binding Precedes High Affinity Aspartate Binding in the Secondary-active Transporter Glt(Ph)

Glt(Ph) from Pyrococcus horikoshii is a homotrimeric Na(+)-coupled aspartate transporter. It belongs to the widespread family of glutamate transporters, which also includes the mammalian excitatory amino acid transporters that take up the neurotransmitter glutamate. Each protomer in Glt(Ph) consists...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Hänelt, Inga, Jensen, Sonja, Wunnicke, Dorith, Slotboom, Dirk Jan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481202/
https://ncbi.nlm.nih.gov/pubmed/25922069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.656876
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