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Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh

Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes is a key mechanism contributing to coupled tra...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Oh, SeCheol, Boudker, Olga
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175574/
https://ncbi.nlm.nih.gov/pubmed/30255846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37291
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