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Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh

Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes is a key mechanism contributing to coupled tra...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Oh, SeCheol, Boudker, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175574/
https://ncbi.nlm.nih.gov/pubmed/30255846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37291
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