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Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh

Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes is a key mechanism contributing to coupled tra...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Oh, SeCheol, Boudker, Olga
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175574/
https://ncbi.nlm.nih.gov/pubmed/30255846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37291
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