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Coupled ion binding and structural transitions along the transport cycle of glutamate transporters

Membrane transporters that clear the neurotransmitter glutamate from synapses are driven by symport of sodium ions and counter-transport of a potassium ion. Previous crystal structures of a homologous archaeal sodium and aspartate symporter showed that a dedicated transport domain carries the substr...

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Bibliografske podrobnosti
Main Authors: Verdon, Grégory, Oh, SeCheol, Serio, Ryan N, Boudker, Olga
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051121/
https://ncbi.nlm.nih.gov/pubmed/24842876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02283
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