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Coupled ion binding and structural transitions along the transport cycle of glutamate transporters

Membrane transporters that clear the neurotransmitter glutamate from synapses are driven by symport of sodium ions and counter-transport of a potassium ion. Previous crystal structures of a homologous archaeal sodium and aspartate symporter showed that a dedicated transport domain carries the substr...

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Autori principali: Verdon, Grégory, Oh, SeCheol, Serio, Ryan N, Boudker, Olga
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051121/
https://ncbi.nlm.nih.gov/pubmed/24842876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02283
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