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Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters

Glutamate transporters are essential players in glutamatergic neurotransmission in the brain, where they maintain extracellular glutamate below cytotoxic levels and allow for rounds of transmission. The structural bases of their function are well established, particularly within a model archaeal hom...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Wang, Xiaoyu, Boudker, Olga
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682989/
https://ncbi.nlm.nih.gov/pubmed/33155546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58417
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