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Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters

Glutamate transporters are essential players in glutamatergic neurotransmission in the brain, where they maintain extracellular glutamate below cytotoxic levels and allow for rounds of transmission. The structural bases of their function are well established, particularly within a model archaeal hom...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Wang, Xiaoyu, Boudker, Olga
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682989/
https://ncbi.nlm.nih.gov/pubmed/33155546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58417
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