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Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue Glt(Tk)

Glutamate transporters catalyse the thermodynamically unfavourable transport of anionic amino acids across the cell membrane by coupling it to the downhill transport of cations. This coupling mechanism is still poorly understood, in part because the available crystal structures of these transporters...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Guskov, Albert, Jensen, Sonja, Faustino, Ignacio, Marrink, Siewert J., Slotboom, Dirk Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110648/
https://ncbi.nlm.nih.gov/pubmed/27830699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13420
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