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Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue Glt(Tk)

Glutamate transporters catalyse the thermodynamically unfavourable transport of anionic amino acids across the cell membrane by coupling it to the downhill transport of cations. This coupling mechanism is still poorly understood, in part because the available crystal structures of these transporters...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Guskov, Albert, Jensen, Sonja, Faustino, Ignacio, Marrink, Siewert J., Slotboom, Dirk Jan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110648/
https://ncbi.nlm.nih.gov/pubmed/27830699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13420
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