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Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue Glt(Tk)

Glutamate transporters catalyse the thermodynamically unfavourable transport of anionic amino acids across the cell membrane by coupling it to the downhill transport of cations. This coupling mechanism is still poorly understood, in part because the available crystal structures of these transporters...

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Pubblicato in:Nat Commun
Autori principali: Guskov, Albert, Jensen, Sonja, Faustino, Ignacio, Marrink, Siewert J., Slotboom, Dirk Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110648/
https://ncbi.nlm.nih.gov/pubmed/27830699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13420
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