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Free Energy Simulations of Ligand Binding to the Aspartate Transporter Glt(Ph)
Glutamate/Aspartate transporters cotransport three Na(+) and one H(+) ions with the substrate and countertransport one K(+) ion. The binding sites for the substrate and two Na(+) ions have been observed in the crystal structure of the archeal homolog Glt(Ph), while the binding site for the third Na(...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218339/ https://ncbi.nlm.nih.gov/pubmed/22098736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.010 |
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