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Free Energy Simulations of Ligand Binding to the Aspartate Transporter Glt(Ph)

Glutamate/Aspartate transporters cotransport three Na(+) and one H(+) ions with the substrate and countertransport one K(+) ion. The binding sites for the substrate and two Na(+) ions have been observed in the crystal structure of the archeal homolog Glt(Ph), while the binding site for the third Na(...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Heinzelmann, Germano, Baştuğ, Turgut, Kuyucak, Serdar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218339/
https://ncbi.nlm.nih.gov/pubmed/22098736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.010
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