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Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein
Two licensed serogroup B meningococcal vaccines contain factor H binding protein (FHbp). The antigen specifically binds human FH, which downregulates complement. In wild-type mice whose mouse FH does not bind to FHbp vaccines, the serum anti-FHbp antibody response inhibited binding of human FH to FH...
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| Publicado en: | mBio |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Microbiology
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479705/ https://ncbi.nlm.nih.gov/pubmed/26106082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00842-15 |
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