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Bactericidal Antibody Responses Induced by Meningococcal Recombinant Chimeric Factor H-Binding Protein Vaccines

Factor H-binding protein (fHbp) is a novel meningococcal vaccine candidate that elicits serum antibodies that activate classical complement pathway bacteriolysis and also inhibit binding of the complement down-regulatory protein, factor H, to the bacterial surface. One limitation of fHbp as a vaccin...

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Detalhes bibliográficos
Main Authors: Beernink, Peter T., Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423104/
https://ncbi.nlm.nih.gov/pubmed/18362128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00033-08
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