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Fine Antigenic Specificity and Cooperative Bactericidal Activity of Monoclonal Antibodies Directed at the Meningococcal Vaccine Candidate Factor H-Binding Protein

No broadly protective vaccine is available for the prevention of group B meningococcal disease. One promising candidate is factor H-binding protein (fHbp), which is present in all strains but often sparsely expressed. We prepared seven murine immunoglobulin G monoclonal antibodies (MAbs) against fHb...

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Detalhes bibliográficos
Main Authors: Beernink, Peter T., Welsch, Jo Anne, Bar-Lev, Michal, Koeberling, Oliver, Comanducci, Maurizio, Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519416/
https://ncbi.nlm.nih.gov/pubmed/18591239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00367-08
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