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Naturally Acquired Passive Protective Activity against Neisseria meningitidis Group C in the Absence of Serum Bactericidal Activity

The hallmark of immunity to meningococcal disease is a bactericidal titer in serum of ≥1:4 measured with human complement, but this threshold titer may underestimate the extent of protection. We used the infant rat model of meningococcal bacteremia to measure group C passive protective activity in s...

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Autori principali: Welsch, Jo Anne, Granoff, Dan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC517551/
https://ncbi.nlm.nih.gov/pubmed/15385492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5903-5909.2004
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