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Recent developments in cell-based assays and stem cell technologies for Botulinum neurotoxin research and drug discovery

Botulinum neurotoxins (BoNTs) are exceptionally potent inhibitors of neurotransmission, causing muscle paralysis and respiratory failure associated with the disease botulism. Currently, no drugs are available to counter intracellular BoNT poisoning. To develop effective medical treatments, cell-base...

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Bibliografiske detaljer
Udgivet i:Expert Rev Mol Diagn
Main Authors: Kiris, Erkan, Kota, Krishna P., Burnett, James C., Soloveva, Veronica, Kane, Christopher D., Bavari, Sina
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478076/
https://ncbi.nlm.nih.gov/pubmed/24450833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737159.2014.867808
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