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A High Content Imaging Assay for Identification of Botulinum Neurotoxin Inhibitors
Synaptosomal-associated protein-25 (SNAP-25) is a component of the soluble NSF attachment protein receptor (SNARE) complex that is essential for synaptic neurotransmitter release. Botulinum neurotoxin serotype A (BoNT/A) is a zinc metalloprotease that blocks exocytosis of neurotransmitter by cleavin...
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| Publicado no: | J Vis Exp |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354101/ https://ncbi.nlm.nih.gov/pubmed/25489815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51915 |
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