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Recent developments in cell-based assays and stem cell technologies for Botulinum neurotoxin research and drug discovery

Botulinum neurotoxins (BoNTs) are exceptionally potent inhibitors of neurotransmission, causing muscle paralysis and respiratory failure associated with the disease botulism. Currently, no drugs are available to counter intracellular BoNT poisoning. To develop effective medical treatments, cell-base...

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Detalhes bibliográficos
Publicado no:Expert Rev Mol Diagn
Main Authors: Kiris, Erkan, Kota, Krishna P., Burnett, James C., Soloveva, Veronica, Kane, Christopher D., Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478076/
https://ncbi.nlm.nih.gov/pubmed/24450833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737159.2014.867808
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