A Herpes Simplex Virus Type 1 Human Asymptomatic CD8(+) T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a “Humanized” HLA Transgenic Rabbit Model

Ítems similars

• HLA-A02:01-Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8(+) T Cells from Seropositive Asymptomatic Individuals and Protect “Humanized” HLA-A*02:01 Transgenic Mice Against Ocular Herpes
  per: Srivastava, Ruchi, et al.
  Publicat: (2015)
• Therapeutic Immunization with a Mixture of Herpes Simplex Virus 1 Glycoprotein D-Derived “Asymptomatic” Human CD8(+) T-Cell Epitopes Decreases Spontaneous Ocular Shedding in Latently Infected HLA Transgenic Rabbits: Association with Low Frequency of Local PD-1(+) TIM-3(+) CD8(+) Exhausted T Cells
  per: Khan, Arif A., et al.
  Publicat: (2015)
• Asymptomatic HLA-A*02:01–Restricted Epitopes from Herpes Simplex Virus Glycoprotein B Preferentially Recall Polyfunctional CD8(+) T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice against Ocular Herpes
  per: Dervillez, Xavier, et al.
  Publicat: (2013)
• A Novel HLA (HLA-A*0201) Transgenic Rabbit Model for Preclinical Evaluation of Human CD8(+) T Cell Epitope-Based Vaccines against Ocular Herpes
  per: Chentoufi, Aziz A., et al.
  Publicat: (2010)
• Future of an “Asymptomatic” T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine
  per: Dervillez, Xavier, et al.
  Publicat: (2012)