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A Herpes Simplex Virus Type 1 Human Asymptomatic CD8(+) T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a “Humanized” HLA Transgenic Rabbit Model
PURPOSE. A clinical vaccine that protects from ocular herpes simplex virus type 1 (HSV-1) infection and disease still is lacking. In the present study, preclinical vaccine trials of nine asymptomatic (ASYMP) peptides, selected from HSV-1 glycoproteins B (gB), and tegument proteins VP11/12 and VP13/1...
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| Publicado en: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477261/ https://ncbi.nlm.nih.gov/pubmed/26098469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17074 |
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