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Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia

During critical periods of development, the brain easily changes in response to environmental stimuli, but this neural plasticity declines by adulthood. By acutely disrupting paired immunoglobulin-like receptor B(PirB) function at specific ages, we show that PirB actively represses neural plasticity...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Bochner, David N., Sapp, Richard W., Adelson, Jaimie D., Zhang, Siyu, Lee, Hanmi, Djurisic, Maja, Syken, Josh, Dan, Yang, Shatz, Carla J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476552/
https://ncbi.nlm.nih.gov/pubmed/25320232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010157
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