Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia

During critical periods of development, the brain easily changes in response to environmental stimuli, but this neural plasticity declines by adulthood. By acutely disrupting paired immunoglobulin-like receptor B(PirB) function at specific ages, we show that PirB actively represses neural plasticity...

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Detaylı Bibliyografya
Yayımlandı:Sci Transl Med
Asıl Yazarlar: Bochner, David N., Sapp, Richard W., Adelson, Jaimie D., Zhang, Siyu, Lee, Hanmi, Djurisic, Maja, Syken, Josh, Dan, Yang, Shatz, Carla J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476552/
https://ncbi.nlm.nih.gov/pubmed/25320232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010157
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