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Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids

The threshold for Hebbian synaptic plasticity in the CNS is modulated by prior synaptic activity. At adult CA3-CA1 synapses, endocannabinoids play a role in this process, but how activity engages and maintains this retrograde signaling system is not well understood. Here we show that conditional del...

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Détails bibliographiques
Publié dans:Mol Psychiatry
Auteurs principaux: Djurisic, Maja, Brott, Barbara K., Saw, Nay L., Shamloo, Mehrdad, Shatz, Carla J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372352/
https://ncbi.nlm.nih.gov/pubmed/29670176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0034-4
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