Neuroprotection from stroke in the absence of MHCI or PirB

Recovery from stroke engages mechanisms of neural plasticity. Here we examine a role for MHC Class I (MHCI) H2-Kb and H2-Db, and PirB receptor. These molecules restrict synaptic plasticity and motor learning in the healthy brain. Stroke elevates not only neuronal expression of H2-Kb and H2-Db, but a...

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Hauptverfasser: Adelson, Jaimie D, Barreto, George E, Xu, Lijun, Kim, Taeho, Brott, Barbara K, Ouyang, Yi-Bing, Naserke, Thorsten, Djurisic, Maja, Xiong, Xiaoxing, Shatz, Carla J, Giffard, Rona G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314229/
https://ncbi.nlm.nih.gov/pubmed/22445338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.01.020
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