Chargement en cours...
N-terminally extended analogues of ShK as potent and selective blockers of the voltage-gated potassium channel Kv1.3
The voltage-gated potassium channel Kv1.3 is an important target for the treatment of autoimmune diseases and asthma. Blockade of Kv1.3 by the sea anemone peptide ShK inhibits the proliferation of effector memory T lymphocytes and ameliorates autoimmune diseases in animal models. However, the lack o...
Enregistré dans:
| Publié dans: | FEBS J |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472561/ https://ncbi.nlm.nih.gov/pubmed/25864722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13294 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|