Učitavanje...
Conformational flexibility in the binding surface of the potassium channel blocker ShK
ShK is a 35-residue peptide that binds with high affinity to human voltage-gated potassium channels through a conserved K-Y dyad. Here we employ NMR measurements of backbone amide (15)N spin relaxation rates to investigate motions of the ShK backbone. Although ShK is rigid on the ps-ns timescale, in...
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| Izdano u: | Chembiochem |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303621/ https://ncbi.nlm.nih.gov/pubmed/25236806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402295 |
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