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LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling

Lipoprotein receptor-related protein 6 (LRP6) plays a critical role in skeletal development and homeostasis in adults. However, the role of LRP6 in mesenchymal stem cells (MSCs), skeletal stem cells that give rise to osteoblastic lineage, is unknown. In this study, we generated mice lacking LRP6 exp...

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Bibliografische gegevens
Gepubliceerd in:Bone Res
Hoofdauteurs: Li, Changjun, Williams, Bart O, Cao, Xu, Wan, Mei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472141/
https://ncbi.nlm.nih.gov/pubmed/26273519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2014.6
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