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Disruption of LRP6 in osteoblasts blunts the bone anabolic activity of PTH
Mutations in Low-density lipoprotein receptor-related protein 6 (LRP6) are associated with human skeletal disorders. LRP6 is required for parathyroid hormone (PTH)-stimulated signaling pathways in osteoblasts. We investigated whether LRP6 in osteoblasts directly regulates bone remodeling and mediate...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787713/ https://ncbi.nlm.nih.gov/pubmed/23609180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1962 |
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