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LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling

Lipoprotein receptor-related protein 6 (LRP6) plays a critical role in skeletal development and homeostasis in adults. However, the role of LRP6 in mesenchymal stem cells (MSCs), skeletal stem cells that give rise to osteoblastic lineage, is unknown. In this study, we generated mice lacking LRP6 exp...

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Bibliografski detalji
Izdano u:Bone Res
Glavni autori: Li, Changjun, Williams, Bart O, Cao, Xu, Wan, Mei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472141/
https://ncbi.nlm.nih.gov/pubmed/26273519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2014.6
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