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Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling

During bone resorption, abundant factors previously buried in the bone matrix are released into the bone marrow microenvironment, which results in recruitment and differentiation of bone marrow mesenchymal stem cells (MSCs) for subsequent bone formation, temporally and spatially coupling bone remode...

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Autori principali: Crane, Janet L., Cao, Xu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904610/
https://ncbi.nlm.nih.gov/pubmed/24487640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70050
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