Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH

Intermittent parathyroid hormone (iPTH) treatment stimulates T-cell production of the osteogenic Wnt ligand Wnt10b, a factor required for iPTH to activate Wnt signaling in osteoblasts and stimulate bone formation. However, it is unknown whether iPTH induces Wnt10b production and bone anabolism throu...

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Detalhes bibliográficos
Main Authors: Bedi, Brahmchetna, Li, Jau-Yi, Tawfeek, Hesham, Baek, Ki-Hyun, Adams, Jonathan, Vangara, Sameera S., Chang, Ming-Kang, Kneissel, Michaela, Weitzmann, M. Neale, Pacifici, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311391/
https://ncbi.nlm.nih.gov/pubmed/22393015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120735109
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