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Disruption of PTH Receptor 1 in T Cells Protects against PTH-Induced Bone Loss
BACKGROUND: Hyperparathyroidism in humans and continuous parathyroid hormone (cPTH) treatment in mice cause bone loss by regulating the production of RANKL and OPG by stromal cells (SCs) and osteoblasts (OBs). Recently, it has been reported that T cells are required for cPTH to induce bone loss as t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924900/ https://ncbi.nlm.nih.gov/pubmed/20808842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012290 |
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