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INHIBITON OF ANTIGEN PRESENTATION AND T CELL CO-STIMULATION BLOCKS PTH INDUCED BONE LOSS
T cells are required for continuous PTH (cPTH) treatment to induce bone loss as they sensitize SCs to PTH through CD40 Ligand (CD40L), a surface molecule of activated T cells. Since CD40L expression is a feature of activated T cells, we investigated whether antigen (Ag) mediated T cell activation is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269765/ https://ncbi.nlm.nih.gov/pubmed/20392239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05216.x |
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