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T CELLS POTENTIATE PTH INDUCED CORTICAL BONE LOSS THROUGH CD40L SIGNALING
PTH promotes bone catabolism by targeting bone marrow stromal cells (SCs) and their osteoblastic progeny. Here we show that a continuous infusion of PTH that mimics hyperparathyroidism fails to induce osteoclast formation, bone resorption and cortical bone loss in mice lacking T cells. T cells provi...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2569843/ https://ncbi.nlm.nih.gov/pubmed/18680714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.07.001 |
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