Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation

Increased production of tumor necrosis factor α (TNF) in the bone marrow (BM) in response to both oxidative stress and T cell activation contributes to the bone loss induced by estrogen deficiency, but it is presently unknown whether oxidative stress causes bone loss through T cells. Here we show th...

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Detalhes bibliográficos
Main Authors: Grassi, Francesco, Tell, Gianluca, Robbie-Ryan, Michaela, Gao, Yuhao, Terauchi, Masakazu, Yang, Xiaoying, Romanello, Milena, Jones, Dean P., Weitzmann, M. Neale, Pacifici, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986617/
https://ncbi.nlm.nih.gov/pubmed/17848519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703610104
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