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Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency

Postmenopausal bone loss stems from the inability of osteoblastic activity to match the increase in osteoclastic bone resorption induced by estrogen deficiency. However, the mechanism that uncouples osteoblast from osteoclast activities remains unexplained. We show that ovariectomy enhances the prod...

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Detalhes bibliográficos
Main Authors: Weitzmann, M. Neale, Roggia, Cristiana, Toraldo, Gianluca, Weitzmann, Louise, Pacifici, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151629/
https://ncbi.nlm.nih.gov/pubmed/12464669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15687
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